Toward Ultrasound-Guided Trans-Perineal High Intensity Focused Ultrasound treatment of Benign Prostatic Hyperplasia - preclinical validation
Introduction and objective: The trans-perineal (TP) approach to the prostate for Ultrasound (US) imaging and for focal therapy using High Intensity Focused Ultrasound (HIFU) offers several advantages over alternatives. TP US-guided HIFU could become a completely non-invasive treatment for Benign Prostatic Hyperplasia (BPH), in contrast to the existing minimally invasive ones.
We present the results of preclinical studies demonstrating US-guided HIFU ablation with real-time tracking of the focal point prior to and during the ablation process.
During preclinical phase of the TP US-guided HIFU ablation system, experimental treatment was suggested to dog owners for dogs diagnosed with prostate cancer. Prior to dog treatment, a safety in-vivo experiment was performed in a pig model.
Conclusions: New HIFU imaging technology provides real-time feedback from the focal point within the body prior to ablation, paving the way for TP non-invasive treatment of BPH.
Sponsor: NINA Medical Ltd.
Journal of Endourology, vol. 37, no. S1 (September 2023)